Non sedating anti histamine

30 Mar

Histamine can cause itching, sneezing, runny nose, and watery eyes.

Also, in some persons histamine can close up the bronchial tubes (air passages of the lungs) and make breathing difficult.

In the fasting state bilastine is quickly absorbed, but the absorption is slowed when it is taken with food or fruit juice.

Therefore, it is recommended that bilastine is taken at least one hour before and no sooner than two hours after a meal.

Please see package insert for additional information and possible updates.

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.

Receptor binding data indicate that at a concentration of 2–3 ng/m L (7 nanomolar), desloratadine shows significant interaction with the human histamine H1-receptor.

Desloratadine inhibited histamine release from human mast cells in vitro.

They work by preventing the effects of a substance called histamine, which is produced by the body.Often referred to as the nonsedating antihistamines.They compete with histamine for histamine receptor type 1 (H1) receptor sites in the blood vessels, GI tract, and respiratory tract, which, in turn, inhibits physiologic effects that histamine normally induces at the H1 receptor sites.Most cases of allergic rhinitis respond to pharmacotherapy.Patients with intermittent symptoms are often treated adequately with oral antihistamines, decongestants, or both as needed.